Great car good on gas. Non smoker very clean. More info Is the 2006 Lexus RX a Good Used Car? Overall Rating 9/10 – Objectively speaking, the 2006 Lexus RX is pretty close to perfect. Interior, Comfort & Cargo 9/10 – This is as close as you’re going to get to a first class flight on four wheels. Reliability 8/10 – The Lexus RX may require specialty service, but you won’t be in the garage all that often, and the SUV has a good chance of reaching 300,000 miles. Safety 8/10 – Anti-lock brakes and traction control come standard, and the car’s crash test ratings are excellent. Gas Mileage 7/10 – 18/24 miles to the gallon, city/highway, isn’t bad for an eighteen-year-old mid-size SUV. Value 7/10 – It’s the best deal you’re likely to find on a luxury mid-size SUV from 2006. Not prohibitively expensive, but it’s still more money than some drivers might be comfortable spending on something this old.